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Lupus Skin Involvement: The Facts

Systemic lupus erythematosus (SLE) is a chronic and sometimes disabling autoimmune disease that can damage any part of the body, frequently attacking the skin, kidneys, joints, and/or nervous system. The Lupus Foundation of America estimates that 1.5 million Americans have lupus.

  • Of individuals with SLE, nearly four out of five will have skin involvement.
  • Skin involvement is quite often the first presenting symptom of SLE.
  • Up to 60% will develop the malar (butterfly) rash.
  • Even more–up to 69%–will develop a sun-sensitive or photosensitive rash, mainly on the areas exposed to UV light (Thomas).

Skin involvement can be acute, subacute, or chronic.

  • Chronic cutaneous lupus erythematosus tends to occur for long periods of time, can leave permanent scarring and color changes to skin, and comes in several forms:
    Discoid lupus erythematosus
    Lupus erythematosus profundus
    Chilblain cutaneous lupus
    Lupus tumidus

All lupus-specific rashes are exacerbated by UV light.

  • Studies initially suggested that UV-B rays (burning rays)were the most dangerous for people with lupus, but more recently, it has become apparent that UV-A rays (aging rays) are also problematic.
  • Individuals with SLE can take preventive measures by avoiding sun exposure and with the awareness that florescent lights also sometimes UV.

Sources
Lahita, R.G. and Phillips, R. H. (1998). Lupus Q&A: Everything You Need to Know. New York, NY: Penguin Group Press.

Thomas, D.E. (2014). The Lupus Encyclopedia. Baltimore, MD: Johns Hopkins Press.

Melissa Davis:
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